Anti-Doping Research Projects Approved for Funding by PCC

2009 Funded Projects

Characterization of the Human Urinary Steroidome
Dr. J. Thomas Brenna of Cornell University
(Continued in 2010)

Longitudinal evaluation of urinary endogenous steroid concentrations
Sports Medicine Research and Testing Laboratory   
(Continued in 2011)

Detection of novel androgenic anabolic activities in urine and serum, a novel approach to detecting steroids based on the androgen receptor
Dr. Fred Schaufele, University of California San Francisco

An investigation of the comparability of oral and urine steroid profiles
Dr. Diana Wilkins, University of Utah

2010 Funded Projects

Analysis of labeled carbohydrate moieties of natural and recombinant peptide hormones by LC/MS/MS
Dr. Vanessa Agon, National Measurement Institute of Australia

Establishment of IRMS 13C/12C reference intervals for improved detection of endogenous steroid use and the development of a sensitive LC/MS/MS method to detect various forms of hCG
Dr. Anthony Butch, University of California Los Angeles

Stable isotope ratio analysis of illicit testosterone preparations
Dr. Michael Collins, National Measurement Institute of Australia

Can genomic analysis be the answer to autologous blood transfusion detection?
Dr. Barbara Daniel, King's College (London)

Effect of intra-muscular and intra-tendious platelet rich plasma injections on systemic concentration of performance enhancing growth factors
Dr. Jason Dragoo, Stanford University

Metabolism of designer steroids and prohormones via the chimeric mouse with humanized liver
Dr. Peter Van Eenoo, DoCoLab, Ghent University

Development of a genotype-based assay for homologous blood doping
Dr. James Rupert, University of British Columbia 

2011 Funded Projects

RT-qPCR approach for detection of recombinant human growth hormone use in athletes      
Dr. David Bruns and Dr. Brian Kelly, University of Virginia

GH-2004: Novel biomarkers for the detection of IGF-1 abuse
Dr. Richard Holt, University of Southhampton

Detection of UDP-Glucuronosyltransferuse B17 inter-individual variations in Peripheral Blood Mononucelar Cells: implications for testosterone catabolism and anti-doping analysis
Dr. Andrew Kicman, King's College (London)

Circulating microRNAs as a stable biomarker for detection of autologous transfusion
Dr. Nicolas Leuenberger, Swiss Laboratory for Anti-Doping Analyses

Synthesis and characterization of human metabolites of toremifene
Dr. Monica Mazzarino, Laboratorio Antidoping FMSI

Structural differences as a biomarker of EPO use
Dr. Pauline Rudd, National Institute for Bioprocessing Research and Training,

Analytical strategy for the search and structural elucidation of non-target compounds
Dr. Grigory Rodchenkov, Moscow Anti-Doping Center

Determination of 2H/1H ratios of endogenous urinary steroids
Dr. Thomas Piper, Swiss Laboratory of Doping Analyses